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FLASH GENE

Symbol

MARCHF8

contributors: mct - updated : 08-02-2023

HGNC name	membrane-associated ring finger (C3HC4) 8
HGNC id	23356

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in non-small cell lung cancer NSCLC tissues compared to adjacent normal lung tissues

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer lung   might be a predictive factor and an attractive therapeutic target for NSCLC patients

ANIMAL & CELL MODELS

March8-deficient mice were less susceptible than their wild-type counterparts to herpes simplex virus 1 (HSV-1) infection