Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

EPOR

contributors: mct - updated : 17-01-2018

HGNC name	erythropoietin receptor
HGNC id	3416

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ECYT1

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       gain of function activated cell proliferation pathways in melanoma cells and resulted in increased cell proliferation and resistance to hypoxia and cisplatin treatment

Susceptibility

Variant & Polymorphism

Candidate gene	unlikely involved in Diamond-Blackfan anemia
Marker
Therapy target
	System Type Disorder Pubmed cardiovascular aquired   EPO/EPOR is a novel therapeutic target in cardiovascular disease

ANIMAL & CELL MODELS

macrophage-specific Epor(-/-) mice developed lupus-like symptoms, and interference in EPO signaling ameliorated the disease progression in lupus-like mice