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FLASH GENE

Symbol

SDC3

contributors: mct - updated : 26 -08 -20

HGNC name	syndecan 3 (N-syndecan)
HGNC id	10660

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	high expression of MDK and SDC3 may contribute to the highly perineural invasion and poor prognosis of human pancreatic cancer
Therapy target
	System Type Disorder Pubmed immunology immunodeficiency   an effective microbicide should target both syndecan-3 and CD209 on dendritic cells to prevent HIV transmission

ANIMAL & CELL MODELS

Syndecan-3(-/-) mice exhibit a novel form of muscular dystrophy characterized by impaired locomotion, fibrosis, and hyperplasia of myonuclei and satellite cells