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FLASH GENE
Symbol CALCRL contributors: mct - updated : 20-12-2018
HGNC name calcitonin receptor-like
HGNC id 16709
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in clear cell renal cell carcinoma, in advanced stages, correlated with high tumor grade and conferred shorter overall survival
tumoral     --over  
in acute myeloid leukemia with increased mortality
Susceptibility
  • to essential hypertension
  • to gestational diabetes (GDM)
  • Variant & Polymorphism SNP
  • 8SNP
  • two CALCRL variants were associated with gestational diabetes (GDM) risk
  • Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancerurinary 
    target for future functional studies and drug development in clear cell renal cell carcinoma
    ANIMAL & CELL MODELS