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FLASH GENE

Symbol

UBE2I

contributors: mct/npt/pgu - updated : 08-04-2016

HGNC name	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
HGNC id	12485

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in advanced melanomas

Susceptibility

to late-onset Alzheimer disease (AD)

Variant & Polymorphism other	UBE2I polymorphisms might be associated with a risk of AD

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer skin   blocking expression of UBE2I sensitizes melanomas to the cytotoxic effects of chemotherapeutic drugs

ANIMAL & CELL MODELS