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FLASH GENE

Symbol

SLC14A1

contributors: mct/shn - updated : 05-10-2013

HGNC name	solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
HGNC id	10918

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

JK

related resource

Blood Group Antigen Mutation Database

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   during chondrogenic differentiation

Susceptibility

. urinary bladder cancer susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Urea permeability is 45-fold lower in erythrocytes from UT-B knockout mice, daily urine output is 1.5-fold greater and urine osmolality is lower than from those in wild-type mice