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FLASH GENE
Symbol SH2D2A contributors: mct - updated : 06-04-2014
HGNC name SH2 domain protein 2A
HGNC id 10821
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
  • to Guillain-Barré syndrome
  • multiple sclerosis
  • Variant & Polymorphism other association with a homozygous genotype for a low repeat number of tandem GA in the SH2D2A gene in Guillain-Barré syndrome
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • Tsad-deficient murine thymocytes failed to respond to CXCL12 with increased Itk phosphorylation, and displayed reduced actin polymerization and cell migration responses