| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| tumoral
| germinal mutation
|
|
|
| |
in ovarian mucinous cystadenoma with uterine and skin leiomyomata and renal cell cancer | | tumoral
| germinal mutation
|
|
| loss of function
|
in hereditary leiomyomatosis and renal cell cancer (HLRCC)  | | tumoral
| germinal mutation
|
|
|
| |
in adult leydig cell tumors of the testis | | tumoral
|
|
| --low
|
| |
FH mRNA and protein expression are reduced in clear cell renal cancer, the most common histologic variant of kidney cancer, and reduced FH leads to the accumulation of HIF2A | |
