| basic FUNCTION
| regulating macrophage migration, phagocytosis, and nitric oxide production |
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involved in the regulation of peripheral macrophage activation  |
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has the potential to modulate inflammatory actions of microglia, which proposes novel aspects for the process of degeneration and/or regeneration of the brain |
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protein regulating the innate immune responses to bacterial ligands and may have a role in the pathogenesis of inflammatory bowel diseases |
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MST1/MST1R signaling seems to play at least some role in the pathogenesis of Merkel cell carcinoma |
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may be one of the major determinants that affects the properties of tumor stroma and that produces a permissive microenvironment to promote cancer metastasis |
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is a positive regulator of mammary gland ductal morphogenesis by controlling overall epithelial cell turnover, macrophage recruitment, and STAT3 activation in the developing mammary gland |
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MST1/MST1R play important roles in inflammation, cell growth, migration, and epithelial to mesenchymal transition during tumor development |
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appears to promote the migration of fibroblasts, enhances collagen synthesis and remodeling, and effectively improves wound healing |
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hepatokine that potentially has a beneficial role in hepatic lipid and glucose metabolism via the activation of AMP-activated protein kinase (AMPK) |
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is an effective inhibitor of inflammation and lipid accumulation in the stressed liver, thereby indicating that it has a key regulatory role in Non-alcoholic steatohepatitis (NASH) |
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MST1 controlled inflammation response and mitochondrial function in endothelial cells |
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MST1 is the primary factors responsible for endothelial cells dysfunction in aneurysms formation through inducing inflammation response, endothelial apoptosis, and NFKB1 signaling pathway activation |
