basic FUNCTION
| catalyzing the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex (the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways) |
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regulating the activity state of the BCKD complex |
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catalyzes the irreversible, rate-limiting step in the catabolism of branched-chain amino acids (BCAAs) |
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integral part of an enzyme complex located in the mitochondrial matrix of many tissues which regulates the levels of the branched-chain amino acids (BCAAs), leucine, isoleucine and valine |