Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TUBA1C contributors: - updated : 23-02-2006
HGNC name tubulin, alpha 1c
HGNC id 20768
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer dimer
HOMOLOGY
interspecies ortholog to murine Tuba6
intraspecies paralog to TUBA3
Homologene
FAMILY tubulin family
CATEGORY structural protein
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
basic FUNCTION
  • major constituent of microtubules, binding two moles of GTP, one at an exchangeable site on the beta chain and one at a nonexchangeable site on the alpha-chain
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component dimer of alpha and beta chains
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    GTP
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in gastric cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS