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FLASH GENE
Symbol HYDIN contributors: mct - updated : 13-10-2012
HGNC name hydrocephalus inducing
HGNC id 19368
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY structural protein
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • potential central pair protein required for ciliary motility
  • axonemal protein, involved in growth and microtubule motility
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ICS19
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • mice with Hydin defects develop lethal hydrocephalus, and hydrocephalus is caused by a central pair defect impairing ciliary motility and fluid transport in the brain