Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CGRRF1 contributors: - updated : 08-01-2004
HGNC name cell growth regulator with ring finger domain 1
HGNC id 15528
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a ring zinc binding C3HC4 RING finger domain
HOMOLOGY
interspecies ortholog to rattus cell growth regulator
Homologene
FAMILY
CATEGORY regulatory , signaling growth factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • primary response gene expressed to moderate levels in functional p53 cells
  • CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS
    text negative regulator of cell proliferation
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    induced by TP53
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS