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FLASH GENE

Symbol

DHDH

contributors: - updated : 29-11-2004

HGNC name	dihydrodiol dehydrogenase (dimeric)
HGNC id	17887

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

no homology with other types of dihydrodiiol dehydrogenase

HOMOLOGY

interspecies	ortholog to japenese monkey,dog,pig,rabbit
	homolog to rattus LOC308583

Homologene

FAMILY

medium chain dehydrogenase/reductase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

intracellular

basic FUNCTION	high carbonyl reductase activity
	NADP(+) dependent oxydation of trans-dihydrodiols of aromatic hydrocarbons to the corresponding catechol

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

detoxification

text	putative detxification enzyme against food-derived reactive dicarbonyl compounds

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule
	NADP+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS