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FLASH GENE
Symbol RNASE2 contributors: - updated : 13-12-2006
HGNC name ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
HGNC id 10045
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • eight cysteine and histidine and lysine residues
  • N-terminal region necessary for mediating chemotactic activity
    • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to murine Rnase2
    Homologene
    FAMILY pancreatic ribonuclease family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm,cytosolic,granule
    text matrix of eosinophil's large specific granule
    basic FUNCTION pyrimidine specific nuclease selectively chemotactic for dendritic cells
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS