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FLASH GENE
Symbol METAP1 contributors: npt - updated : 03-01-2008
HGNC name methionyl aminopeptidase 1
HGNC id 15789
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal extended strings of basic and acidic residues
  • a C terminal catalytic domain
    • HOMOLOGY
    Homologene
    FAMILY
  • peptidase M24A family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • protecting the alpha subunit of eIF from inhibitory phosphorylation
  • removing the N-terminal MET residue from nascent proteins
    • CELLULAR PROCESS protein, post translation
    protein, degradation
    protein, translation regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Co2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS