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FLASH GENE
Symbol JPH3 contributors: npt/mct - updated : 11-03-2009
HGNC name junctophilin 3
HGNC id 14203
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • C terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows affinity to the plasma membrane
    • HOMOLOGY
    interspecies homolog to murine Jph3
    Homologene
    FAMILY
  • junctophilin gene family
    • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    basic FUNCTION
  • mediating cross-talk between cell surface and endoplasmic reticulum
  • involved in the formation of junctional membrane structures
    • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the junctional membrane complexes
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) HDL2
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS