Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol PIK3C2A contributors: - updated : 03-05-2005
HGNC name phosphoinositide-3-kinase, class 2, alpha polypeptide
HGNC id 8971
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • lipid kinase catalytic domain
  • one px (phox homology) domain
  • a C terminal C2 domain
    • HOMOLOGY
    interspecies homolog to murine Pik3c2a
    Homologene
    FAMILY phosphoinositide 3-kinase (PI3K) family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • synthesis of phosphatidylinositide 3-phosphates
  • may be involved in integrin-dependent signaling
    • CELLULAR PROCESS cell life, differentiation
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling signal transduction
    intracellular signaling cascade
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by insulin
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS