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FLASH GENE
Symbol CDIPT contributors: - updated : 24-06-2005
HGNC name CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
HGNC id 1769
EXPRESSION
Type widely
constitutive ofúLUNG AND BRAIN.
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen   lowly
 thymus   lowly
Cardiovascularheart   lowly
Digestiveintestinelarge intestinecolon lowly
 intestinesmall intestine  lowly
 liver   highly
Endocrinepancreas   lowly
Nervousbrain   lowly
Reproductivefemale systemovary  lowly
 male systemtestis  lowly
 male systemprostate  lowly
Respiratorylung   lowly
Urinarykidney   lowly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
Muscularstriatumskeletal  
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text placenta lowly,kidney and liver
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to goat polledness and intersexuality gene
homolog to Drosophila CG9245
homolog to C.elegans Y46G5A.5
Homologene
FAMILY member of the CDP-alcohol phosphatidyl transferase class-I family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
intracellular,cytoplasm,organelle,Golgi
text an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus
basic FUNCTION having both phosphatidylinositol synthase and phosphatidylinositol :inositol exchange activity
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS cellular trafficking transport
text phosphatidylinositol transporter
PATHWAY
metabolism lipid/lipoprotein
signaling
phospholipid biosynthesis
a component
INTERACTION
DNA
RNA
small molecule metal binding, cofactor,
magnesium Mg2+,manganese Mn2+
protein
cell & other
REGULATION
inhibited by phosphatidylinositol,phosphatidylinositol phosphate and nucleoside di- and tri- phosphates
calcium Ca2+ and zinc Zn2+
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS