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FLASH GENE
Symbol ISLR contributors: - updated : 20-08-2007
HGNC name immunoglobulin superfamily containing leucine-rich repeat
HGNC id 6133
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine  highly
Lymphoid/Immunespleen   highly
Reproductivefemale systemovary  highly
 female systemuterus  highly
Visualeyeretina   
cells
SystemCellPubmedSpeciesStageRna symbol
Visualcone photoreceptor
Visualganglion cell
Visualrod photoreceptor
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a leucine-rich repeat, with conserved flanking sequences
  • an immunoglobulin Ig-like
  • a transmembrane domains
    • HOMOLOGY
    Homologene
    FAMILY immunoglobulin superfamily (containing a leucine rich repeat)
    CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION involved in cell adhesion
    CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) BBS4
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS