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FLASH GENE

Symbol

RPL7A

contributors: - updated : 26-02-2004

HGNC name	ribosomal protein L7a
HGNC id	10364

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies	ortholog to murine Rpl7a
	homolog to Drosophila RpL7A
	homolog to C.elegans Y24D9A.4a

Homologene

FAMILY

L7AE family of ribosomal proteins

CATEGORY

RNA associated

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic,ribosome

basic FUNCTION

inhibiting the ability of a subclass of nuclear hormone receptors including thyroid hormone receptor to transactivate by preventing their binding to their DNA response elements

CELLULAR PROCESS

protein, translation/synthesis

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

ribosomal protein being a component of the 60S subunit

INTERACTION

DNA

RNA

binding

small molecule

protein

binding to a subclass of nuclearhormone receptors including thyroid hormone receptor

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS