Selected-GenAtlas references SOURCE GeneCards NCBI Gene Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol EIF3CL contributors: KTN/npt - updated : 26/11/2008
HGNC name eukaryotic translation initiation factor 3, subunit C-like
HGNC id 26347
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineneuroendocrinepituitary  moderately
 thyroid   highly
Reproductivefemale systemuteruscervix highly
 female systemovary  highly
Skin/Tegumentskin   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose  highly
cell lineage
cell lines
fluid/secretion moderately in lymph
at STAGE
physiological period fetal
Text predominantly in umbilical cord
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a PCI domain
    • HOMOLOGY
    interspecies homolog to dog EIF3CL (98.6 pc)
    homolog to cow EIF3CL (98.1 pc)
    homolog to rattus Eif3c (96.4 pc)
    homolog to murine Eif3c (96.9 pc)
    homolog to chicken EIF3CL (93.2 pc)
    Homologene
    FAMILY
  • eIF-3 subunit C family
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • promoting the binding of methionyl-tRNAi and mRNA
  • involved in regulation of translational initiation
    • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to the 40S ribosome
  • interacting with EIF3K
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS