Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CARS2 contributors: KTN/npt - updated : 30/10/2008
HGNC name cysteinyl-tRNA synthetase 2, mitochondrial (putative)
HGNC id 25695
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   moderately
Digestiveintestine   moderately
 liver   highly
 stomach   moderately
Lymphoid/Immunespleen   highly
 thymus   highly
Reproductivefemale systemovary  moderately
 female systemuteruscervix highly
 male systemprostate  highly
Respiratorylung   highly
Skin/Tegumentskin   moderately
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose  moderately
Connectivebone  moderately
Muscular   moderately
cell lineage
cell lines
fluid/secretion highly in lymph and blood
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to dog CARS2 (81.9 pc)
homolog to chimpanzee CARS2 (92.8 pc)
homolog to cow CARS2 (75.9 pc)
homolog to murine Cars2 (79.5 pc)
homolog to chicken CARS2 (66.9 pc)
Homologene
FAMILY
  • class-I aminoacyl-tRNA synthetase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • acting as a cysteine-tRNA ligase
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    cysteinyl-tRNA aminoacylation
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, nucleotide,
  • Zn2+ (one ion per subunit)
  • ATP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS