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FLASH GENE
Symbol POLR2J contributors: - updated : 22-03-2006
HGNC name polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
HGNC id 9197
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
RNA polymerase Rpb3/Rpb11 dimerization domain
mono polymer heteromer , dimer
HOMOLOGY
interspecies homolog to murine Polr2j
homolog to rattus LOC288588
intraspecies homolog to RASA4
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION subunit of RNA polymerase II, catalyzing the transcription of DNA into RNA
CELLULAR PROCESS nucleotide, transcription
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism purine/pyrimidine
signaling
a component
INTERACTION
DNA binding
RNA
small molecule
protein interacting with POLR2C
cell & other
REGULATION
repressed by doxorubicin treatment
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS