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FLASH GENE
Symbol NDNL2 contributors: - updated : 23-08-2007
HGNC name necdin-like 2
HGNC id 7677
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
Endocrineadrenal gland   highly
 parathyroid   highly
Reproductivemale systemtestis   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  highly
cell lineage
cell lines
fluid/secretion
at STAGE
IMPRINTING paternally
text likely maternally expressed like the neighbour UBE3A gene
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a MAGE domain
HOMOLOGY
interspecies ortholog to 76p100 identical to the murine Mage-g1 protein
intraspecies homolog to NDN
Homologene
FAMILY necdin/MAGE gene family
CATEGORY signaling growth factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION growth suppressor that facilitates the entry of the cell into cell cycle arrest
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein binds the C-terminus of E2F1 and NGFR
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS