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FLASH GENE
Symbol ADAMTS15 contributors: npt/ - updated : 26-09-2002
HGNC name ADAM metallopeptidase with thrombospondin type 1 motif, 15
HGNC id 16305
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialabsorptive excretory   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • ADAM cystein-rich domain
  • thrombospondin type 1 domain
    • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to C.elegans R10H10.1
    Homologene
    FAMILY
  • ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family
  • reprolysin family zinc metalloprotease
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in intestinal epithelial cells wound-healing processes and may have important pathophysiological roles in intestinal cells
    • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS