Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ZRSR2 contributors: mct - updated : 05-11-2012
HGNC name zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
HGNC id 23019
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • arginine-serine rich domain
  • a RNA-recognition motif
  • two C3H1-type zinc fingers
  • mono polymer heteromer , dimer
    HOMOLOGY
    interspecies homolog to murine U2af1rs2
    intraspecies homolog to U2AF1L1
    Homologene
    FAMILY
  • zinc finger protein family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • splicing factor activity
  • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • of the spliceosome
  • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • specifically interacting with the large subunit of the U2AF heterodimer
  • physically interacts with U2AF2, as well as SRSF1 and SRSF2, with a distinct function from its homologue, U2AF1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral germinal mutation      
    in myelodysplasia
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS