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FLASH GENE

Symbol

GNGT1

contributors: mct/npt - updated : 01-06-2016

HGNC name	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
HGNC id	4411

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	restricted

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine pancreas         Reproductive female system placenta       Visual eye retina

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

embryo

Text	expressed in the developing retina (Chen 2007)

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

G protein gamma family

CATEGORY

receptor membrane G

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,nucleus

basic FUNCTION

retinal rod phosphoreceptor, involved as a modulator or transducer in various transmembrane signaling systems

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

3 units, alpha, beta and gamma

INTERACTION

DNA

RNA

small molecule

protein

GNGT1, GNG2, GNB1, GNB2, GNB3, interacts with MTOR and promotes its activation

cell & other

REGULATION

inhibited by

TH (Liu 2007)

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS