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FLASH GENE

Symbol

RNF10

contributors: mct - updated : 07-04-2007

HGNC name	ring finger protein 10
HGNC id	10055

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive mouth       highly Lymphoid/Immune thymus       highly Nervous brain       highly Reproductive male system testis     highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

N- terminal region, containing the RING finger domain (ring finger motif, C3HC4 type), not essential for the binding to MEOX2

conjugated

MetalloP

HOMOLOGY

interspecies

homolog to murine Rnf10

Homologene

FAMILY

RING finger protein family

CATEGORY

regulatory , transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,chromatin/chromosome

basic FUNCTION	having a ring finger motif, which is known to be involved in protein-protein interactions
	regulates MAG expression and is required for myelin formation

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	zinc Zn2+

protein

binding to MEOX2

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS