protein
| coregulating CCNB1 with CDKN1A |
|
physically interacts with CFTR (strong inhibition of CFTR chloride current by syntaxin 8 overexpression) |
|
endosomal SNARE proteins physically and functionally interact with CFTR |
|
directly interacts with HECTD3 and the overexpression of HECTD3 promotes the ubiquitination of STX8 |
|
strong interaction between ERRFI1 and STX8 upon ligand activation therefore ensures recruitment of internalized EGFR to late endosomes and subsequently the lysosomal degradation compartment |
|
partners of CLN8 are VAPA, C14orf1/hERG28, STX8, GABARAPL2, BNIP3 and BNIP3L proteins and are associated with biologically relevant processes such as synthesis and transport of lipids, vesicular/membrane trafficking, autophagy/mitophagy and apoptosis |
|
STX8 interacts with the acid-sensitive potassium channel KCNK3, and regulates the endocytosis of KCNK3 |
|
STX8 facilitates NTRK1 transport from the Golgi to the plasma membrane and regulates the surface levels of NTRK1 but not NTRK2 receptors |