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FLASH GENE

Symbol

B4GALT4

contributors: mct/npt - updated : 27/09/2008

HGNC name	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
HGNC id	927

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

text	variants 1 and 2 encode the same protein

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 9 - 2366 40 344 - Clark (2003) variant 2 8 - 2283 40 344 - Clark (2003)

EXPRESSION

Type	ubiquitous

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart         Digestive esophagus       highly   mouth       highly Nervous brain         Reproductive female system ovary         female system uterus         male system testis       Respiratory respiratory tract trachea     highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum cardiac     Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

pregnancy

Text	highly in placenta

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus

conjugated

GlycoP

HOMOLOGY

Homologene

FAMILY

glycosyltransferase 7 family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm,organelle,membrane
	intracellular,cytoplasm,organelle,Golgi
text	trans Golgi
	type II transmembrane glycoprotein

basic FUNCTION	involved in glycosphingolipid biosynthesis
	involved in the N-linked oligosaccharide biosynthesis cooperatively but not in a redundant manner with beta-1,4-GalT I within cells

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

lipid/lipoprotein

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS