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FLASH GENE
Symbol ZNF174 contributors: npt - updated : 07-05-2009
HGNC name zinc finger protein 174
HGNC id 12963
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 2498 46.3 407 - Williams (1995)
3 - 1593 26.7 234 - Williams (1995)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
 thymus    
Cardiovascularheart    
Digestiveintestinesmall intestine   
 intestinelarge intestinecolon  
Endocrinepancreas    
Nervousbrain    
Reproductivefemale systemovary   
 male systemtestis  moderately
 male systemprostate   
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • C2H2 type, Krüppel-like, DNA binding protein
  • a leucine rich region
  • a SCAN domain found in the three zinc finger motifs, capable of mediating the dimerization of a large family of zinc-finger transcription factors
  • conjugated MetalloP
    mono polymer homomer , dimer
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • potential transcriptional repressor involved in regulation of transcription, DNA-dependent
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS