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FLASH GENE
Symbol MTMR3 contributors: npt/ - updated : 28-03-2006
HGNC name myotubularin related protein 3
HGNC id 7451
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
20 - 8924 130.4 1170 - Zhao (2000)
19 - 8897 129.3 1161 - Zhao (2000)
20 - 9008 133.5 1198 - Zhao (2000)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveliver    
Endocrinepancreas    
Nervousbrain    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumcardiac  
Muscularstriatumskeletal  
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • region similar to the active site of tyrosine phosphatases
  • a double-helical motif similar to the SET interaction domain
  • a FYVE domain at C-terminus
  • HOMOLOGY
    interspecies homolog to C.elegans y60a3a.16
    intraspecies homolog to myotubularin protein 3
    Homologene
    FAMILY
  • protein-tyrosine phosphatase family
  • non-receptor class myotubularin subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • protein tyrosine/serine/threonine phosphatase
  • putatively involved in signal transduction
  • CELLULAR PROCESS protein, post translation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • phosphatidylinositol (3)-phosphate
  • cell & other
    REGULATION
    inhibited by sodium vanadate and pervanadate,ph dependency
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS