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FLASH GENE
Symbol HTR1A contributors: mct - updated : 26-08-2008
HGNC name 5-hydroxytryptamine (serotonin) receptor 1A
HGNC id 5286
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 1269 - 422 - Kato (2008)
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainlimbic systemhippocampus  
cells
SystemCellPubmedSpeciesStageRna symbol
Nervouspyramidal cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor
conjugated GlycoP
HOMOLOGY
interspecies ortholog to rattus Htr1a
ortholog to murine Htr1a
ortholog to dog Htr1a
Homologene
FAMILY G protein coupled receptor superfamily
CATEGORY receptor membrane G
SUBCELLULAR LOCALIZATION     plasma membrane
text
  • integral to plasma membrane
  • basic FUNCTION
  • inhibiting adenylate cyclase
  • functions as a neurotransmitter, a hormone, and a mitogen
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS