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FLASH GENE

Symbol

PRR5L

contributors: mct - updated : 09-05-2012

HGNC name	proline rich 5 like
HGNC id	25878

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001160167 9 - 3979 NP_001153639 - 368 - 2012 21964062 NM_024841 10 - 3965 NP_079117 - 368 - 2012 21964062 NM_001160168 6 - 3378 NP_001153640 - 240 - 2012 21964062 NM_001160169 7 - 3588 NP_001153641 - 205 - 2012 21964062

EXPRESSION

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION

basic FUNCTION

AKT1S1 and PRR5L are novel MTOR-associated proteins that control the balance between cell growth and cell death

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein	binds specifically to CTRC2, via Rictor and/or SIN1
	associates with ZFP36 to accelerate ZFP36-mediated mRNA turnover and functionally links the control of ZFP36-regulated mRNA stability to MTORC2 activity (

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS