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Symbol IQCJ-SCHIP1 contributors: mct/npt - updated : 12-09-2022
HGNC name IQCJ-SCHIP1 readthrough
HGNC id 38842
RNA
TRANSCRIPTS type
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
11 - 2391 - 563 - 2015 25950943
10 - 2310 - 536 - 2015 25950943
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
CATEGORY structural protein
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm
basic FUNCTION
  • is a cytoplasmic protein present in axon initial segments and nodes of Ranvier
  • IQCJ-SCHIP1 contributes to nodal membrane-associated cytoskeleton organization, likely through its interactions with the ANKG/betaIV-spectrin network
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • CK2-regulated IQJC-SCHIP-1 association with ANK3 contributes to axon initial segment (AIS) maintenance
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS