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FLASH GENE

Symbol

ACSM2A

contributors: KTN/npt - updated : 25-06-2008

HGNC name	acyl-CoA synthetase medium-chain family member 2A
HGNC id	32017

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ACSM2A 15 - 2969 64 577 - -

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive liver       highly Lymphoid/Immune tonsils       moderately Reproductive female system breast mammary gland   moderately Urinary kidney       predominantly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

mono polymer

monomer

HOMOLOGY

interspecies	homolog to dog ACSM2A (79 pc)
	homolog to murine Acsm2a (76.3 pc)

Homologene

FAMILY

ATP-dependent AMP-binding enzyme family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria,matrix

basic FUNCTION	acting as a medium-chain fatty acid : CoA ligase
	acting on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

lipid/lipoprotein

signaling

fatty acid and lipid metabolism

a component

INTERACTION

DNA

RNA

small molecule	cofactor, nucleotide,
	Mg2+
	Mn2+
	ATP

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS