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FLASH GENE
Symbol SYT14 contributors: mct - updated : 17-10-2016
HGNC name synaptotagmin 14
HGNC id 23143
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 5213 - 517 - 2007 17304550
9 - 5186 - 619 - 2007 17304550
9 - 5129 - 600 - 2007 17304550
9 - 5069 - 574 - 2007 17304550
8 - 5008 - 555 - 2007 17304550
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland    
Nervousbrainlimbic systemhippocampus  
 brainbasal nucleicaudate nucleus  
 brainbasal nucleicorpus callosum  
Reproductivefemale systemovary   
Respiratoryrespiratory tracttrachea   
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one C2 domain
  • a single transmembrane domain at the N-terminus
  • a putative fatty-acylation site just downstream of the transmembrane domain
  • mono polymer oligo
    HOMOLOGY
    interspecies homolog to murine Syt14
    homolog to drosophila Strep14
    Homologene
    FAMILY synaptotagmin family
    CATEGORY transport
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    basic FUNCTION
  • required for synaptic vesicle and secretory granule exocytosis
  • may be involved in membrane trafficking in specific tissues outside the brain
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS exocytosis transport
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other Ca2+ dependent
    ASSOCIATED DISORDERS
    corresponding disease(s) SCAR11
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS