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FLASH GENE
Symbol ABCC10 contributors: - updated : 10-06-2006
HGNC name ATP-binding cassette, sub-family C (CFTR/MRP), member 10
HGNC id 52
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
Lymphoid/Immunetonsils   highly
Reproductivefemale systemovary  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two ATP binding domains
  • three transmembrane (3TM) domains (transmembrane helices arranged in three membrane spanning domains)
    • HOMOLOGY
    interspecies ortholog to murine Abcc10
    Homologene
    FAMILY ATP binding cassette superfamily, subfamily C (CFTR/MRP)
    CATEGORY signaling , transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION involved in multi-drug resistance
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text amphipathic anions transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS