basic FUNCTION
| protein kinase, non catalytic subunit, involved in fatty acid and cholesterol metabolism |
|
having a function that allows the regulation of proteasomal activity under conditions of energy demand |
|
regulating cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase |
|
and hormone- sensitive lipase |
|
regulates the activation of TSC2 by phosphorylating TSC2 |
|
phosphorylating GFPT1 at Ser243 (has an important role in the regulation of the GFPT1 enzymatic activity) |
|
may be implicated in the pathogenesis of chronic intestinal inflammatory conditions, such as inflammatory bowel disease |
|
energy-sensing enzyme, counteracting energy depletion by stimulation of energy production and limitation of energy utilization |
|
having a critical role in the survival of circulating erythrocytes |
|
stimulates energy production and limits energy utilization |
|
may act as a modulator in airway inflammation, such as acute lung injury or cystic fibrosis |
|
implicated in modulation of glucose and fatty acid metabolism |
|
induces MUC5B expression through the MAPK14 signaling pathway in airway epithelial cells |
|
PRKAB1-induced MUC5B expression may be regulated through the MAPK14 signaling pathway in human airway epithelial cells |
|
involved in the pathogenesis of Alzheimer disease |
|
CAMKK2 and PRKAB1 function in a signaling pathway that participates in the regulation of adiposity |
|
critical roles in regulating growth and reprogramming metabolism, and has recently been connected to cellular processes such as autophagy and cell polarity |