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FLASH GENE
Symbol CFAP47 contributors: mct - updated : 23-03-2021
HGNC name cilia and flagella associated protein 47
HGNC id 28546
DNA
TYPE functioning gene
STRUCTURE 465.58 kb     64 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
16 - 3611 110.3 976 - 2021 33472045
64 - 9941 - 3187 - 2021 33472045
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   moderately
Reproductivemale systemtestis    Homo sapiens
Respiratoryrespiratory tracttrachea  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
CATEGORY motor/contractile
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • cilia- and flagella-associated protein
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • potential interaction and/or inter-regulation between CFAP65 and CFAP47 during spermiogenesis
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) SPGFX3
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • in Cfap47-mutated mouse model, the adult males of which were sterile and presented with reduced sperm motility and abnormal flagellar morphology and movement