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FLASH GENE
Symbol LONRF1 contributors: mct - updated : 26-12-2022
HGNC name LON peptidase N-terminal domain and ring finger 1
HGNC id 26302
DNA
TYPE functioning gene
STRUCTURE 33.62 kb     12 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
12 - 3585 - 762 - 2009 19028597
12 - 3618 - 773 - 2009 19028597
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY tumor suppressor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • LONRF1, CDK1, RPL18, GNB2L1 (RACK1), RPL30, and SEC61A1 are crucial components in the diagnosis and treatment of Prostate carcinoma
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in prostate carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
  • reliable molecular biomarker for the diagnosis of prostate carcinoma
  • Therapy target
    ANIMAL & CELL MODELS