basic FUNCTION
| involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling |
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putative adapter localizing LIM-binding proteins, via its PDZ domain,to actin filaments of both skeletal muscle and non muscle tissues |
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essential positive regulator of osteoblast differentiation and maturation and bone formation |
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potentially plays a role in odontoblast differentiation and dentin matrix mineralization of human teeth with normal and pathologic conditions |
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has multiple functions including regulating mesenchymal stem cell (MSC) osteogenesis |
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downstream gene of TGF-beta1, involved in periodontal ligament cell proliferation |
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is involved in the premature calvarial ossification in sporadic craniosynostoses |
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is a positive regulator of RET through blocking of CBLC-mediated ubiquitination and degradation |