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FLASH GENE
Symbol PANK3 contributors: - updated : 28-01-2006
HGNC name pantothenate kinase 3
HGNC id 19365
DNA
TYPE functioning gene
STRUCTURE 23.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
text structure six exons for the core protein
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Pank3
intraspecies paralog to panks
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • First committed step of universal CoA biosunthesis
  • catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5) and derivatives
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism vitamin
    signaling
    regulatory enzyme of CoA biosynthesis
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS