| basic FUNCTION
| mediating the axonal transport of at least 1 class of vesicles by interacting directly with kinesin light chain |
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sperm-associated JNK-binding protein, having a functional role in sperm-egg fusion |
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involvement of SPAG9 mediated signal transduction pathways in reproductive processes |
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its expression may play a role in cellular growth and thyroid carcinogenesis  |
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may have a role in tumor development and early spread and thus could serve as a novel target for early detection and for cancer immunotherapy |
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acts together with MAPK8IP3 to promote presynaptic assembly |
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novel role of a scaffolding protein SPAG9 in the regulation of surface CD40 expression and fine-tuning of dendritic cells function |
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MAPK8IP3 and SPAG9 are critical and functionally redundant in cytokinesis and control ARF6 localization to the midbody by forming a tripartite complex of MAPK8IP3/SPAG9, active ARF6, and kinesin-1 |
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novel role of SPAG9 scaffold protein in the bridging of CD40LG-triggered CD40 internalization and CD40-dependent signaling in splenic B lymphocytes |
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MAPK8IP3, SPAG9 are positive regulators of kinesin-1-dependent axonal transport, which prevents neuronal degeneration |
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SPAG9 and MAPK8IP3 play critical roles in kinesin-1-dependent axonal transport, which prevents brain neuronal degeneration |
