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FLASH GENE
Symbol S100A5 contributors: - updated : 26-02-2004
HGNC name S100 calcium binding protein A5
HGNC id 10495
Location 1q21      Physical location : 153.509.623 - 153.514.241
Synonym symbol(s) S100D
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 4.00 kb     4 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
urinarykidneyascending thicklimb   
Urinarykidneytubuleconvoluted tubuledistal tubule 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two calcium binding domains with an EF-hand motif,
  • one S100 specific Nter,
  • one classical Cter
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • playing an inherent functional role to the post-thick ascending limb of Henle portion in the nephron
  • having calcium ion binding activity.
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • constituent of epidermal differentiation complex
    • INTERACTION
    DNA
    RNA
    small molecule metal binding,
    calcium Ca2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS