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FLASH GENE

Symbol

TCFL5

contributors: npt/ - updated : 12-09-2007

HGNC name	transcription factor-like 5 (basic helix-loop-helix)
HGNC id	11646

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	20q13.3      Physical location : 61.472.467 - 61.493.115
Synonym name	HPV-16 E2 binding protein 1
	Cha transcription factor
Synonym symbol(s)	E2BP-1, Figlb, CHA, MGC46135

DNA

TYPE	functioning gene
STRUCTURE	20.65 kb     6 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed TCFL5 6 - 2474 52.6 500 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart         Nervous brain         Reproductive male system testis         male system prostate       Respiratory lung         Urinary kidney

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage	specifically of primary spermatocytes
cell lines
fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES		basic
STRUCTURE

motifs/domains

a basic helix-loop-helix (HLH) motif

HOMOLOGY

Homologene

FAMILY

basic helix-loop-helix (BHLH) family of transcription factors

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION

regulating transcription associated with growth and differentiation

CELLULAR PROCESS	cell life, differentiation
	cell life, proliferation/growth
	nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

development

text	spermatogenesis

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS