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FLASH GENE
Symbol HIST1H2BJ contributors: - updated : 12-02-2004
HGNC name histone 1, H2bj
HGNC id 4761
Location 6p21.33      Physical location : 27.100.095 - 27.100.575
Synonym name H2B histone family, member R
Synonym symbol(s) H2B/r,H2BFR
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text belonging to a microcluster located between the main terminal and proximal clusters on chromosome 6p
STRUCTURE 0.00 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter (CAAT box) (TATA box)
text structure GACTTC element
MAPPING cloned Y linked N status confirmed
regionally located in a microcluster of histone genes on chromosome 6p21.33
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES basic
STRUCTURE
motifs/domains
mono polymer heteromer , octamer
HOMOLOGY
interspecies homolog to C.elegans C50F4.5
Homologene
FAMILY H2B histone family
CATEGORY DNA associated , transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,chromatin/chromosome,nucleosome
basic FUNCTION
  • playing a role in the compacting of DNA into nucleosomes
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of nucleosomes
    INTERACTION
    DNA approximatively 0.146 kb
    RNA
    small molecule
    protein
  • H2A
  • H2B
  • H3
  • H4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS