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FLASH GENE

Symbol

POU5F1B

contributors: mct/ - updated : 10-02-2011

HGNC name	POU class 5 homeobox 1B
HGNC id	9223

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	8q24.21      Physical location : 128.427.856 - 128.429.439
Synonym name	octamer-binding transcription factor 3, pseudogene 1
	POU domain, class 5, transcription factor 1 pseudogene 1
	POU domain transcription factor OCT4-pg12
	POU 5 domain protein
Synonym symbol(s)	OTF3C, OTF3P1, POU5F1P1, POU5F1P4, OCT4-PG1

DNA

TYPE	functioning gene
STRUCTURE	1.60 kb     1 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001159542 1 - 1599 NP_001153014 - 359 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive male system prostate       Homo sapiens

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY	POU transcription factor family
	class-5 subfamily

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION

acts as a transcriptional activator and regulates the expression in a similar way to the POU5F1

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in prostate carcinoma

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS