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FLASH GENE
Symbol CLEC17A contributors: SGE/npt - updated : 17-08-2009
HGNC name C-type lectin domain family 17, member A
HGNC id 34520
Location 19p13.12      Physical location : 14.693.895 - 14.721.951
Synonym name prolectin
Synonym symbol(s) FLJ45910
DNA
TYPE functioning gene
STRUCTURE 28.06 kb     12 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
12 - 1996 - 289 - Graham 2009
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneB cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
Homologene
FAMILY
CATEGORY receptor membrane
SUBCELLULAR LOCALIZATION     plasma membrane
text expressed on a specialized population of proliferating B cells in germinal centers (Graham 2009)
basic FUNCTION
  • receptor expressed on the cell surface but doesn't mediate endocytosis of neoglycoprotein ligand (Graham 2009)
  • has the potential to function in carbohydrate-mediated communication between cells in the germinal center (Graham 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with signaling molecules like GRB2 (Graham 2009)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS